Actua Objective Our goal was to investigate the effect of an intervention, on the injury prevalence density, expressed as the total number of sports and work related injuries relatively to 1000h of time of exposure. Results Poisson distribution showed a significant (p=0.047) lower injury prevalence density in the intervention group (0.510, CI 0.282-0.921) compared to the control group (1.083, CI 0.610-1.699). The greatest impact of the intervention was found in non-contact injuries, with a significant (p=0.007) higher injury prevalence density of non-contact injuries in control (0.855) compared to intervention group (0.185). Discussion and conclusion. This is the first RCT study in PETs proving that a multifactorial injury preventive intervention, with main focus on intrinsic strategies, is effective. Also, the population of PETs is representative for a group participating in multiple sports and few injury preventive studies were conducted in this population. References 1. Sandmark et al (1999). Appl Ergon. 30(5): 435-442. 2. Pihl et al. (2002). J Sports Med Phys Fitness. 42:466-71. 3. Vercruysse et al., in submission 4. Deci & Ryan (2000). The Am psychologist. 55(1): 68-78. 5. Chan & Hagger (2012). J Sci Med Sport. 15(5): 398-406. Effect of beta-alanine and L-histidine supplementation on muscle carnosine loading Blancquaert, L., Everaert, I., Baguet, A., Derave, W. Department of Movement and Sports Sciences, GHENT University (Ghent, Belgium) Abstract Carnosine (β-alanyl-L-histidine) occurs in high concentrations in human skeletal muscle where it works as a proton buffer (Derave et al, 2010). Studies on different animal species reported that beta-alanine and/or L-histidine supplementation are able to increase muscle carnosine and/or anserine content (Tamaki et al., 1977; Dunnett and Harris (1999) and park et al., 2013). In humans, Harris et al (2006) showed that chronic oral beta-alanine supplementation can elevate muscle carnosine content. However, the effect of L-histidine was never established. Therefore, the aims of this study were to investigate the effect of betaalanine and L-histidine supplementation, alone and combined, on human muscle carnosine loading. 15 male and 15 female participants (age: 20.0 ± 2.4 yr, body weight: 66.0 ± 10.6 kg) were divided in three groups (n=10). Each group was supplemented with either pure beta-alanine (BA) (6g/day), L-histidine hydrochloride monohydrate (HIS) (4.7g/day) or both amino acids (BA+HIS). Before and after 23 days of supplementation, carnosine content was evaluated in soleus and gastrocnemius medialis muscles by 1H-MRS. 42 Sport & Geneeskunde | juli 2015 | nummer 2 Pagina 41

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